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Pronounced: pro-ME-tree-um
Generic name: Progesterone
Most important fact about this drug
Prometrium increases the risk of blood clots, which can lead to
phlebitis, breathing problems, vision problems, or stroke. If you
experience any symptoms that might suggest the onset of a
clot-related disorder--pain with swelling, warmth, and redness in a
leg vein, coughing or shortness of breath, loss of vision or double
vision, migraine, or weakness or numbness in an arm or leg--stop
taking Prometrium and see your doctor immediately.
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The FDA is notifying you that the companies that
manufacture and distribute pergolide have agreed to withdraw this drug
from the market due to the potential for heart valve damage. Two new
studies showed that patients with Parkinson’s disease who were treated
with pergolide had an increased chance of serious damage to their heart
valves when compared to patients who did not receive the drug.
Pergolide is a member of a class of drugs known as dopamine agonists
and is used with levodopa and carbidopa to manage the signs and
symptoms (tremors and slowness of movement) of Parkinson’s disease.
Patients with Parkinson’s disease who are taking pergolide should:
- Contact their healthcare professional to discuss alternate treatment options.
- NOT stop taking Pergolide
without consulting their healthcare professional, since stopping
pergolide too quickly can be dangerous and several other effective
treatments are available.
 
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